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The researchers are happy, their universities and institutes have obtained more money for their impressive advances, the industry is bulging with profits and the patients are dying. When you combine this with some of the other actions that Merck has engaged in (which have been discussed in detail on this site) and some of which has been revealed in e-mails published by the Wall Street Journal, it paints a bigger picture. It has nothing whatsoever to do with enhancing human health. Pharmaceutical companies wouldn't spend billions of dollars on direct-to-consumer advertising if it didn't work. Health Care Meltdown by Robert H Lebow MD, page 149 Most, but not all, megasites support themselves with ads for prescription drugs, vitamins, and medical sundries, as well as laptops, life insurance, and books — typical Internet commerce. These advertisements contribute to rising costs by inducing consumer demand for newer, higher-priced drugs, when the older ones may work just as well. In another Kaiser study, co-sponsored by The NewsHour with Jim Lehrer, nearly half of American consumers said they trust advertisements to provide them with accurate information. Vioxx sales shot up 360 percent." The smoking industry is too vast and the number of smokers wishing to quit too lucrative for smoking to be overlooked as a medical problem. They have sophisticated pharmacoeconomic teams to negotiate the presence of their products on the formulary, and they have understood how to use both legislative action and sophisticated marketing to ensure that their products are not cut out of either Medicaid or private sector formularies." Similarly, Johnson and Johnson purchased the advertising space of an entire issue of Newsweek. Suddenly it became a normal part of our everyday experience to be confronted with the idea that we or a loved one might be suffering from ED (erectile dysfunction, for those not in the know), arthritis pain, high cholesterol, nasal congestion, osteoporosis, heartburn, or even the heartbreak of toenail fungus. Through a series of maneuvers including a new rating system for medical schools aimed at eliminating homeopathic colleges, the practice of homeopathy had nearly disappeared as a force in American medicine by 1930. Death By Medicine by Gary Null PhD, page 10 Yet doctors repeatedly make new drugs bestsellers within months." Disease Prevention And Treatment by Life Extension Foundation, page 725 At first, pharmaceutical companies stepped up advertising, some of which ran for four pages, in the medical journals and weekly magazines sent to doctors' offices. These are very expensive ads. Aids A Second Opinion by Gary Null PhD with James Feast, page 265 Fishbein was the most powerful man in American medicine in his day. But the rules were strict, and the content of the ads was, therefore, limited: Drugs could be mentioned by name, but advertisements that discussed the treatment of specific conditions were required to include a lengthy list of side effects and contraindications (situations in which the drug should not be used)." These groups, often led by financially conflicted physicians, sponsor ventures such as pamphlets, brochures, pocket books, Web sites, and registries, and they have gotten out of hand, often subtly recommending off-label drugs and promoting expensive drugs. David Graham (senior drug safety researcher at the FDA) was conducted by Manette Loudon, the lead investigator for Dr. DR.” Since you've made that statement, has anything changed within the FDA to fix what's broken and, if not, how serious is the problem that we're dealing with here.