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Since then, pharmaceutical advertising has grown to an entirely new, pop culture-savvy level. So, how is direct-to-consumer advertising so effective in a system in which doctors write out the prescriptions. Pharmaceutical companies are willing to spend this kind of advertising money on only their most recently approved medication.D.I. Paid advertisements from pharmaceutical companies in the AMA's journal were the AMA's main source of revenue (as it is today). For example, a former editor of the Journal of the American Medical Association (JAMA) alleged that Pfizer, a major pharmaceutical company, had withdrawn $250,000 worth of advertising because an article appearing in JAMA had cast one of their drugs in an unfavorable light. In 1985, the PAC teamed up with the FDA to solicit funds from the pharmaceutical industry for the purpose of combating medical quackery.